Using computer simulations, UO Biochemist Mike Harms and graduate researcher Zach Sailer thought that they could manipulate a protein one mutation at a time and predict its evolution. They failed, but the team harvested information that may be useful for understanding problems such as antibiotic resistance.
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A discovery in Marina Guenza‘s UO chemistry lab that was recently published in a major physics journal, Physical Review Letters, is already being tapped by outside scientists working on a new medical treatment for tuberculosis.
Read the paper:
Physical Review Letters : Universality and Specificity in Protein Fluctuation Dynamics
Read more about the lab’s discovery:
A new anti-inflammatory drug moving into phase two clinical trials to treat two serious diseases was built on a scientific collaboration with UO chemist, Bruce Branchaud.
Read more in AroundtheO and the Daily Emerald: