Biochemists have made a discovery that sheds light on the molecular machinery that allows some cells, such as immune cells or even malignant cancer cells in humans, to wiggle their way through tissues like organs, skin or bones.
The work, conducted in the University of Oregon laboratory of Brad Nolen, a professor in the Department of Chemistry and Biochemistry, was described in a paper in the Feb. 13 issue of the Proceedings of the National Academy of Sciences.
Read more here
The Editors of The Journal of Chemical Physics have chosen a recently accepted article about research in the Andrew H. Marcus‘ lab as an “Editor’s Pick.”
The article, titled “Temperature-dependent conformations of exciton-coupled Cy3 dimers in double-stranded DNA,” was a collaborative effort led by the Marcus group, is also featured on the cover of the journal’s February 28, 2018 edition.
Read more in the JCP
Biochemistry majors Tristan Mistkawi and Alex Egdell are among nine UO undergraduate researchers awarded minigrants through the Undergraduate Research Opportunity Program (UROP), a unit within the Office of the Vice President for Research and Innovation. The $1000 awards are given to students to assist with research expenses including purchasing supplies and materials and paying for travel that is necessary to conduct research.
Tristan is conducting research in the Haley lab on electronic properties of indenofluorenes and their derivatives, and Alex is in the Jasti lab doing reasearch focused on the synthesis of alkyne substituted cycloparaphenylenes for conjugated polymers. Both scholars will present their research at the UO Undergraduate Research Symposium on May 17, 2018.
One of the most widely used drugs to fight cancer could become more effective and safer, based on findings emerging from the lab of UO chemist Vickie DeRose.
In two recently published papers, separate projects using different approaches and led by two of DeRose’s doctoral students have made new predictions for where the platinum-carrying drug cisplatin binds in cells.
Read more about the DeRose Lab’s research and its implications for cancer treatment in AroundtheO
Read more about Prof. Hendon and his research in AroundtheO’s article: Dr. Coffee
Using computer simulations, UO Biochemist Mike Harms and graduate researcher Zach Sailer thought that they could manipulate a protein one mutation at a time and predict its evolution. They failed, but the team harvested information that may be useful for understanding problems such as antibiotic resistance.
Read the full article in AroundtheO
A discovery in Marina Guenza‘s UO chemistry lab that was recently published in a major physics journal, Physical Review Letters, is already being tapped by outside scientists working on a new medical treatment for tuberculosis.
Read the paper:
Physical Review Letters : Universality and Specificity in Protein Fluctuation Dynamics
Read more about the lab’s discovery: