Investigating the Viability of a Carbon Nanotube Surface as a Gastric Cancer Screening Tool

Presenter(s): Bri McAllister—Biology

Faculty Mentor(s): Bree Mohr, Benjamín Alemán

Session: Prerecorded Poster Presentation

Gastric cancer affects the stomach, esophagus, and duodenum . Its presence is often asymptomatic until reaching advanced stages of the disease . By the time they were officially diagnosed, around 50% of patients’ cancer had progressed beyond the locoregional area and only 50% could have a curative resection . Current diagnostic techniques for gastric cancer include endoscopy and a barium swallow study, both with their own faults . Endoscopy is a highly invasive and costly procedure and a barium study tends to be inaccurate . This study aims to evaluate the effectiveness in gastric cancer cell entrapment with a carbon nanotube (CNT) substrate . We patterned a silicon substrate with a checkerboard carbon nanotube surface and seeded on two gastric cell lines in decreasing densities and counted the overall capture rate on both materials . Overall, the results indicate that there may be preferential entrapment at a specific range for fully adherent gastric cancer cells .

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