Organic Synthesis

Phosphine Ligand Synthesis
Phosphines are an essential piece of many modern catalysts. The phosphine ligand has dramatic electronic and steric influences of the metal center that are essential for selectivity and activity. Traditional phosphine syntheses suffer from low yields and limited substrate scopes due to a lack of variety in synthetic routes. We are currently exploring phosphorus chemistry that avoids air- water- and silica-sensitive intermediates to synthesize new and useful phosphine ligands:

ab Flow Ozonolysis
We are currently investigating the effects of shear-force on flow ozonolysis chemistry. Specifically, we are looking to use our film shear reactor to study interesting phenomena such as the solvent cage effect and its influence on ozonolysis product distribution.