Welcome!
The Molecular Muscle Physiology Lab is in the Department of Human Physiology at the University of Oregon. Our lab takes a systems-level approach to chart the signaling networks that regulate mitochondrial function, which in turn governs metabolism in health, aging, and disease. We are also interested in dissecting how exercise positively changes mitochondrial function and how it affects skeletal muscle and heart. We use cutting-edge biological tools to investigate a range of model organisms, from mice to humans. Our research has led to the creation of innovative methodologies, including multi-layered, cross-species genetics/omics gene mapping techniques. This has significantly advanced our understanding of how signaling pathways influence mitochondrial function, quality control, and metabolism. While we explore fundamental biomedical questions, we strongly emphasize innovation. My scientific background supports translating our findings into new preventive and therapeutic strategies for common conditions such as type 2 diabetes, frailty, and obesity.
We believe talent doesn’t exist—only passion does. The most outstanding figures in every field, from sports to science, didn’t start with talent; they developed it through passion. Passion is what drives us, pushing our minds, bodies, and souls to the limit. It transforms into talent through dedication and perseverance.
At our lab, we believe science is for everyone. Science is for you! Interested in joining us? Please contact Dr. Wagner S. Dantas (wdantas[at]uoregon.edu) about graduate student and other research opportunities in the lab. I am accepting graduate students through the Department of Human Physiology Research PhD Program. Please e-mail me if you are interested.