Full text | Loes, Andrea N., Jamie T. Bridgham, and Michael J. Harms. “Coevolution of the Toll-like receptor 4 complex with calgranulins and lipopolysaccharide.” Frontiers in immunology 9 (2018): 304. |
Full text | Wheeler LC, Anderson JA, Morrison AJ, Wong CE, Harms MJ. “Conservation of specificity in two low-specificity proteins” Biochemistry. ASAP. 10.1021/acs.biochem.7b01086 |
Full text | Wheeler LC, Harms MJ. “Human S100A5 binds Ca2+ and Cu2+ independently” BMC Biophysics. 10:8 https://doi.org/10.1186/s13628-017-0040-y |
Full text | Sailer ZR, Harms MJ. “Molecular ensembles make evolution unrpredictable” (2017). Proceedings of the National Academy of Sciences, USA. doi:10.1073/pnas.1711927114 |
Full text | Sailer ZR, Harms MJ. “High-order epistasis shapes evolutionary trajectories.” (2017). PLOS Computational Biology. 13(5):e1005541. |
Full text | Sailer ZR, Harms MJ. “Detecting High-Order Epistasis in Nonlinear Genotype-Phenotype Maps.” (2017). Genetics, 205(3):1079–1088. |
Full text | Eick GN, Bridgham JT, Anderson DP, Harms MJ, Thornton JW. “Robustness of Reconstructed Ancestral Protein Functions to Statistical Uncertainty” (2017). Molecular Biology and Evolution. 34(2):247–261 |
Full text | Lim SA, Hart KM, Harms MJ, Marqusee S. “Evolutionary trend toward kinetic stability in the folding trajectory of RNases H.” (2016). Proceedings of the National Academy of Sciences, USA, 113(46):13045–13050. |
Full text | Wheeler LC, Donor MT, Prell JS, Harms MJ. “Multiple Evolutionary Origins of Ubiquitous Cu2+ and Zn2+ Binding in the S100 Protein Family.” (2016). PLoS ONE. 11(10): e0164740 |
Full text | Wheeler LC, Lim SA, Marqusee S, Harms MJ. “The thermostability and specificity of ancient proteins.” (2016). Current Opinion in Structural Biology. 38:37-43 |
Full text | Hart KM, Harms MJ, Schmidt BH, Elya C, Thornton JW, Marqusee S. “Thermodynamic System Drift in Protein Evolution.” (2014). PLoS Biology. 12(11):e1001994 |
Full text | Harms MJ & Thornton JW. “Historical contingency and its biophysical basis in glucocorticoid receptor evolution.” (2014). Nature. doi:10.1038/nature13410 |
Full text | Harms MJ & Thornton JW. “Evolutionary biochemistry: Revealing the historical and physical causes of protein function.” (2013). Nature Reviews Genetics. 14(8):559-571 |
Full text | Harms MJ, Eick GN, Goswami D, Colucci JK, Griffin PR, Ortlund EA, Thornton JW. “Biophysical mechanisms for large-effect mutations in the evolution of steroid hormone receptors.” (2013) Proceedings of the National Academy of Sciences, USA. 110(28):11475–11480 |
Full text | Williams SG, Harms MJ, Hall KB. “Resurrection of an Urbilaterian U1A/U2B”/SNF protein.” (2013) Journal of Molecular Biology. 425(20):3846–3862 |
Full text | Eick GN, Colucci J, Harms MJ, Ortlund EA, Thornton JW. “Evolution of minimal specificity in the steroid receptors.” (2012) PLoS Genetics. 8(11):e1003072 |
Full text | Harms MJ, Schlessman JL, Sue GR, García-Moreno E. B. “Arginine is ionized at internal positions in a protein.” (2011) Proceedings of the National Academy of Sciences, USA. 108(47):18954-9. Listed as “Must Read” on Faculty of 1000. |
Full text | Bridgham JT, Eick G, Larroux C, Deshpande K, Harms MJ, Gauthier MEA, Ortlund EA, Degnan BM, Thornton JW (2010). “Protein evolution by molecular tinkering: diversification of the nuclear receptor superfamily from a ligand-dependent ancestor.” PLoS Biology 8(10): e1000497 |
Full text | Harms MJ, Thornton JW. (2010). “Analyzing protein structure and function using ancestral gene reconstruction.” Current Opinions in Structural Biology. 20(3):360-366. |
Full text | Harms MJ, Castañeda CA, Schlessman JL, Sue GR, Isom DG, Cannon BR, García- Moreno E. B. (2009). “The pKa values of acidic and basic residues buried at the same internal location in a protein are governed by different factors.” Journal of Molecular Biology. 389:34-47. Listed as “Must Read” on Faculty of 1000. |
Full text | Thesis. Harms, MJ. “Molecular determinants of pKa values of internal ionizable groups in staphylococcal nuclease.” The Johns Hopkins University, ProQuest, UMI Dissertations Publishing, 2009. 3339887. |
Full text | Harms MJ, Schlessman JL, Chimenti MS, Sue GR, Damjanovic A, García-Moreno E. B. (2008). “A buried lysine that titrates with a normal pKa: Role of conformational flexibility at the protein–water interface as a determinant of pKa values.” Protein Science. 17:833-845. |
Full text | Hays FA, Teegarden A, Jones ZJR, Harms MJ, Raup D, Watson F, Cavaliere E, Ho PS. (2005). “How sequence defines structure: a crystallographic map of DNA structure and conformation.” Proceedings of the National Academy of Sciences USA. 102(20):7157-7162. |
Full text | Harms MJ, Wilmarth PA, Kapfer DM, Steel EA, David LL, Bachinger HP, Lampi KJ. (2003). “Laser light-scattering evidence for an altered association of βB1- crystallin deamidated in the connecting peptide.” Protein Science. 13:678-686. |