The DeRose lab had three new publications in 2019, check them out below!
First, a review of current and emerging methods to track platinum anticancer drugs in cells, in a special issue of Inorganica Chimica Acta.
Sutton, E. C.; McDevitt, C. E.; Yglesias, M. V.; Cunningham, R. M.; DeRose, V. J. Tracking the Cellular Targets of Platinum Anticancer Drugs: Current Tools and Emergent Methods. Inorganica Chim. Acta 2019, 118984. https://doi.org/10.1016/j.ica.2019.118984.
Second, an examination of phenanthriplatin-like compounds and their ability to induce nucleolar stress in mammalian tissue culture, in the Journal of Biological Inorganic Chemistry.
McDevitt, C. E.; Yglesias, M. V.; Mroz, A. M.; Sutton, E. C.; Yang, M. C.; Hendon, C. H.; DeRose, V. J. Monofunctional Platinum(II) Compounds and Nucleolar Stress: Is Phenanthriplatin Unique? JBIC J. Biol. Inorg. Chem. 2019, https://doi.org/10.1007/s00775-019-01707-9.
Third, an investigation into the structural properties of platinum compounds responsible for nucleolar stress induction, in the Journal of the American Chemical Society.
*Sutton, E. C.; *McDevitt, C. E.; Prochnau, J. Y.; Yglesias, M. V.; Mroz, A. M.; Yang, M. C.; Cunningham, R. M.; Hendon, C. H.; DeRose, V. J. Nucleolar Stress Induction by Oxaliplatin and Derivatives. J. Am. Chem. Soc. 2019, 141 (46), 18411–18415. https://doi.org/10.1021/jacs.9b10319.