Archived Discussion Topics

July 15, 2021 Nickel-catalyzed asymmetric cross-coupling of a-chloroesters with (hetero)aryl iodides

  • Main paper: https://pubs.rsc.org/en/content/articlelanding/2021/sc/d1sc00822f#!divAbstract
  • Additional paper: https://onlinelibrary.wiley.com/doi/full/10.1002/anie.201914175
  • Discussion handout

July 8, 2021 A molecular endless (74) knot

  • Main paper: https://www.nature.com/articles/s41557-020-00594-x
  • Additional paper: https://www.nature.com/articles/s41557-020-00630-w
  • Discussion handout

May 21, 2020 Photoredox-enabled nucleophilic (radio)fluorination 

  • Main paper: https://pubs.acs.org/doi/full/10.1021/jacs.0c03125
  • Discussion handout coming soon

May 14, 2020 Cheminformatics

May 7, 2020 Development of an automated kinetic profiling system for reaction optimization

  • Main paper: https://pubs.rsc.org/en/content/articlelanding/2019/re/c9re00086k/unauth#!divAbstract
  • Discussion handout

April 30, 2020 Light-driven expansion of spiropyran hydrogels

April 23, 2020 Biomimetic combs as antiadhesive tools

April 16, 2020 Urea-catalyzed functionalization of unactivated C-H bonds

  • Main paper: https://chemrxiv.org/articles/Urea-Catalyzed_Functionalization_of_Unactivated_C_H_Bonds/11886789
  • Discussion handout

April 9, 2020 Co-catalyzed conversion of CO2 to CO

April 2, 2020 Metal-organic cages as “masks” for regioselective C60 functionalization

  • Main paper: https://www.sciencedirect.com/science/article/pii/S2451929419304644
  • Discussion handout

March 4, 2020 Molecular knots

  • Main paper: https://onlinelibrary.wiley.com/doi/full/10.1002/anie.201803871

February 26, 2020 Metal-organic coordination cages as porous ionic liquids

  • Main paper: https://www.nature.com/articles/s41557-020-0419-2

February 19, 2020 Organic photoredox catalysis for 18F labeling 

  • Main paper: https://science.sciencemag.org/content/364/6446/1170

February 12, 2020 Ni-hydride catalyzed HAT to form gem-difluoroalkenes

February 5, 2020 OPRD Synthesis of Ubrogepant

  • Main paper: https://pubs.acs.org/doi/10.1021/acs.oprd.7b00293
  • Supporting paper: https://www.nejm.org/doi/pdf/10.1056%2FNEJMoa1813049
  • Discussion handout

January 29, 2020 Host-guest induced electron transfer for catalysis using metal-organic cages

  • Main paper: https://doi.org/10.1021/jacs.9b11273

January 22, 2020 Redox reactions and mechanochemistry 

  • Main paper: https://science.sciencemag.org/content/366/6472/1500/tab-pdf

January 15, 2020 Photoredox and cross-coupling dual catalysis 

  • Main paper: https://onlinelibrary.wiley.com/doi/full/10.1002/anie.201911109

December 11, 2019 Ladderene polymers

  • Main paper: https://science.sciencemag.org/content/357/6350/475
  • Supporting paper: https://pubs.acs.org/doi/10.1021/jacs.9b01736

December 3, 2019 Photoredox chemistry for late-stage fluorination

  • Main paper: https://www.nature.com/articles/s41557-019-0353-3

November 26, 2019 Planar chirality

  • Main paper: https://pubs.acs.org/doi/10.1021/jacs.9b00941

November 19, 2019 Mechanically triggered small molecule release

  • Main paper: https://pubs.acs.org/doi/10.1021/jacs.9b08663

November 12, 2019 Anti-aromatic metal organic cage

  • Main paper: https://www.nature.com/articles/s41586-019-1661-x
  • Handout: Click Here

November 5, 2019 Ni-catalyzed remote carboxylation

  • Main paper: https://www.nature.com/articles/nature22316
  • Supporting paper: https://doi.org/10.1021/jacs.7b07637

October 29, 2019 Silver-catalyzed hydroalkylation of alkynes 

  • Main paper: https://pubs.acs.org/doi/10.1021/jacs.9b09336

October 22, 2019 Electrochemically-promoted Ni-catalyzed Mizoroki Heck Coupling Reactions

  • Main paper: https://pubs.acs.org/doi/pdf/10.1021/acscatal.9b02230

October 15, 2019 Intramolecular oxidative amination

  • Main paper: https://doi.org/10.1021/jacs.7b01016

September 25, 2019 Palladium catalyzed cycloadditions

  • Main paper: https://pubs.acs.org/doi/10.1021/jacs.8b12636

September 18, 2019 N-N bond formation through dehydrogenative coupling 

September 11, 2019 Synthesis of E-olefins through radical mechanism

September 4, 2019 Redox-Neutral Organometallic Mitsunobu Reactions

August 28, 2019 Electrochemically Enabled Carbohydroxylation of Alkenes

August 21, 2019 Rh-Catalyzed Ethylene Insertion

August 14, 2019 Möbius Aromaticity and Chirality Transfers 

August 7, 2019 Photoene Reactions 

  • Main paper: https://pubs.acs.org/doi/10.1021/jacs.8b08100
  • Main paper correction: https://pubs.acs.org/doi/10.1021/jacs.9b07787
  • Supporting paper: https://pubs.acs.org/doi/10.1021/acs.accounts.6b00357
  • Discussion handout

July 31, 2019 Cyclic Voltammetry 

July 24, 2019 pH-Sensitive DNA Nanoswitches 

  • Main paper: https://doi.org/10.1021/ja500619w
  • Supporting paper: https://doi.org/10.1021/jacs.9b04168
  • Discussion handout

July 17, 2019 Rotaxane Based Mechanophores 

  • Main paper: https://doi.org/10.1021/jacs.7b12405
  • Supporting paper: https://doi.org/10.1021/acscentsci.9b00173
  • Discussion handout

July 10, 2019 Concerted SNAr Reactions

  • Main paper: https://doi.org/10.1038/s41557-018-0079-7
  • Supporting paper: https://doi.org/10.1038/nature17667
  • Discussion handout

July 3, 2019 Strained Cyclic Allenes 

  • Main paper: https://doi.org/10.1038/s41557-018-0080-1 (co-authored by UO alum Evan Darzi!)
  • Supporting paper: https://doi.org/10.1002/anie.201900503
  • Discussion handout

June 26, 2019 Aliphatic Carbonyl-Olefin Metathesis

  • Main paper: https://pubs.acs.org/doi/10.1021/jacs.8b11840
  • Supporting papers:
    • https://pubs.acs.org/doi/10.1021/jacs.7b05641
    • https://www.nature.com/articles/nature17432
  • Follow up paper: EPR tutorial https://pubs.rsc.org/en/content/articlelanding/2018/CS/C6CS00565A#!divAbstract
  • Discussion handout

June 19, 2019 Frustrated Lewis-Base Pairs in Borylation Catalysis